What are polyclonal antibodies?

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Polyclonal antibodies are a type of antibody response generated by multiple B cell clones, rather than from a single clone. This means they are produced in response to various epitopes on the same antigen, resulting in a mixture of antibodies that may have different specificities but recognize the same pathogen.

The choice indicating that polyclonal antibodies are produced naturally during infection reflects the diverse response of the immune system when faced with complex antigens, providing a robust defense against a variety of pathogens. During an immune response, many B cells are activated, each producing its own antibodies against the non-specific features of the pathogen, thus leading to a polyclonal response.

Other options may not fully capture the nature of polyclonal antibodies:

  • Antibodies from a single B cell clone describe monoclonal antibodies, which are derived from one B cell and thus are identical.

  • Antibodies used for cloning may refer to specific techniques that utilize antibodies but don't describe their production or the nature of polyclonal antibodies.

  • Antibodies that target specific pathogens could apply to both polyclonal and monoclonal antibodies, making it an insufficient descriptor.

The essence of polyclonal antibodies lies in their generation from multiple sources, ensuring a broad and effective

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