Which is a potential consequence of excessive glycogen storage?

Excessive glycogen storage can lead to hyperglycemia, which is the condition characterized by an abnormally high level of glucose in the bloodstream. When the body stores more glycogen than it can effectively use, particularly in the liver and muscle tissues, it can result in elevated blood sugar levels. This can happen due to an inability to properly metabolize glucose, often as a result of insulin resistance or other metabolic dysfunctions.

In individuals with conditions like glycogen storage diseases, the excess glycogen can lead to complications affecting glucose homeostasis, which manifests as hyperglycemia. Conversely, hypoglycemia refers to low blood sugar levels, muscle atrophy relates to muscle wasting due to inadequate nutrition or disuse, and fatigue can result from many physiological factors but is not directly a consequence of excessive glycogen storage.